SAN ANTONIO

The San Antonio Spurs were in a tough spot after Kawhi Leonard hurt his ankle in the second half.

That’s when Danny Green and the Spurs’ supporting cast stepped up.

Green scored seven of his 16 points in overtime, helping

San Antonio top James Harden and the Houston Rockets 110-107 on Tuesday night to take a 3-2 lead in their second-round playoff series.

Harden had 33 points, 10 rebounds and 10 assists. He had a chance at a potential tying 3-pointer in the final seconds of OT, but was blocked from behind by Manu Ginobili.

Leonard had 22 points and 15 rebounds in 38 minutes before exiting with an injured right ankle. He stepped on Harden’s foot while running back in transition with 5:37 left in the third quarter and then played limited minutes before sitting out overtime.

The Spurs already were without Tony Parker, who will miss the rest of the playoffs after surgery to repair a ruptured left quadriceps tendon.

“It was frustrating because I wanted to play,” Leonard said. “But I was happy seeing my teammates out there putting in a good effort and getting the win.”

Leonard said he will play in Game 6 on Thursday in Houston.

Green made a go-ahead 3- pointer and converted a three-point play to make it 109-107 Spurs with 30.1 seconds left. He also made a foul shot down the stretch to help San Antonio hold on.

“I think we all made a decision to be aggressive,” Green said of Leonard’s absence, “regardless of what was going to happen. We weren’t going to lose the game being on our heels.”

Two questionable plays closed regulation with the game tied at 101.

Harden was whistled for a charge after dribbling all but a few seconds off the shot clock before driving to the basket on Jonathon Simmons. The Spurs failed to take a shot on their final possession, with Mills banking in a 3-pointer after the buzzer sounded.

Harden also played solid defense, helping hold Leonard and LaMarcus Aldridge to 15-for-42 shooting as he rotated assignments in Houston’s smaller lineup.

“I was trying to keep them in front of me,” Harden said. “Two All-Stars and even Pau (Gasol), who is 7-foot-something. I just tried to be aggressive and do the best that I can and help my team.”