Moments after Chris Sale joined Fenway Park fans in a show of respect of Adam Jones, the Boston ace escalated the feud with Baltimore star Manny Machado.

Sale stepped off the mound to let a standing ovation build in the first inning Tuesday night as Jones approached the plate, a day after he was racially taunted at the ballpark.

But when Machado came up next, Sale threw a pitch behind his legs. After the Red Sox won 5-2, Machado was irate — and Sale unapologetic.

“I lost my respect for that organization, Boston and how they’re handling that whole situation,” Machado said in an expletive-filled rant. “If they’re going to hit me, hit me. Go ahead. Get it over with. Don’t keep lingering it around and doing that. I’ve lost mad respect for that team and that organization,” he said.

Jones, meanwhile, acknowledged the reception from the fans and Sale’s reaction. Earlier in the day, the Orioles center fielder received a personal apology from Red Sox team president Sam Kennedy on behalf of the club.

After Sale threw behind Machado, plate umpire D.J. Reyburn immediately issued a warning to both teams. Orioles manager Buck Showalter came out for a lengthy discussion with Reyburn, Boston manager John Farrell remained in his dugout.

Sale (2-2) struck out the side in the first, getting Jones and Machado, and fanned 11 in eight innings.

Machado hit a ball completely out of the park for the second straight night, connecting off Sale in the seventh.

Hanley Ramirez homered twice for Boston. The Red Sox also hit into a bizarre triple play that began when shortstop J.J. Hardy had a popup fall behind him in shallow left field.

Sale gave up three hits. Craig Kimbrel got three straight outs for his AL-leading ninth save in 10 chances.

Betts hit a two-run double.