ANAHEIM, Calif. (AP) — Mike Trout greeted Brad Boxberger with a three-run walkoff homer to cap a fourrun ninth inning and give the Los Angeles Angels a 6-5 victory over the Tampa Bay Rays on Thursday night in the opener of a four-game series.

Rays closer Grant Balfour came on in the ninth to try and protect a 5-2 lead for Erik Bedard, but walked his first two batters before giving up an RBI single by Collin Cowgill. Trout jumped on a 1-1 pitch from Boxberger (0-1) and drove it into the top tier of the double decker bullpen in left field for his eighth homer.

Fernando Salas (3-0) pitched a perfect inning to get the victory.

Blue Jays 4, Indians 2

TORONTO (AP) — Edwin Encarnacion hit two home runs, Juan Francisco also connected and Toronto gave manager John Gibbons his 400th career win.

Encarnacion hit a solo homer in the second off Danny Salazar and added a two-run blast in the fifth off C.C. Lee. It was his second multihomer game of the season and the 13th of his career.

Encarnacion finished 3 for 4, adding a double in the third.

Two batters after Encarnacion’s homer in the second, Francisco also went deep off Salazar (1-4) , who lost for the fourth time in seven starts.

David Murphy homered for the Indians, whose streak of series victories was snapped at three.

Orioles 2, Royals 1

KANSAS CITY, Mo. (AP) — Nelson Cruz homered and Baltimore snapped a fourgame losing streak to remain first in the AL East.

Cruz homered in the fourth after Chris Davis drew a walk to lead off the inning. It was Cruz’s 12th home run, which is second in the American League to the 15 of Chicago White Sox rookie Jose Abreu. Cruz’s 35 RBIs are tied for second in the AL.

Wei-Yin Chen (5-2) limited the Royals to one run and seven hits over 5.1 innings with one walk and one strikeout. Chen, who is 5-1 in his past seven starts, was removed in the sixth after Salvador Perez walked and Alex Gordon singled with one out. Darren O’Day replaced Chen and struck out Danny Valencia and retried Johnny Giavotella on a fly to right.