Brandon Lowe of the Rays is congratulated by Austin Meadows after hitting a two-run homer in the second inning Wednesday night against the Red Sox. Tampa Bay won, 9-5. Michael Dwyer/Associated Press

BOSTON — Blake Snell pitched five shutout innings and the Tampa Bay Rays backed him with a trio of 400-foot homers to beat the Boston Red Sox 9-5 on Wednesday night and earn their fifth straight victory.

Willy Adames, Brandon Lowe and Yoshi Tsutsugo all homered off Zack Godley, and Austin Meadows hit a solo shot in the ninth after Boston scored five in the eighth to cut into an eight-run deficit.

Lowe had a single, homer and double in his first three at-bats but failed in his next two plate appearances to complete the cycle.

J.D. Martinez hit a grand slam to make it 8-5 as Boston’s first six batters in the eighth hit safely off Aaron Slegers. But Nick Anderson came on and struck out the next two batters, and then after Alex Verdugo singled to bring the potential tying run to the plate, Jackie Bradley Jr. grounded out to end the inning.

The Red Sox have lost three in a row and eight of their last 11.

Kevin Pillar had four hits for Boston, but he also misplayed a fly ball that led to two runs and got thrown out trying to take second on a ball off the Green Monster with the Red Sox trailing 6-0.

Snell (1-0) allowed four hits and walked no one, striking out six to earn his first win of the season. The 2018 AL Cy Young winner, who struggled with injuries last year, threw a season-high 70 pitches and left with an 8-0 lead.

“Looking forward to being a starting pitcher again and getting away from the opener role,” Snell said. “I felt like Blake Snell. I finally feel healthy.”

Manager Kevin Cash called it “another step in the right direction.”

“Blake’s got to feel good with this one,” he said.

Godley (0-2) hadn’t allowed a run in eight innings over two previous Fenway appearances. He was charged with eight runs on 10 hits and two walks, striking out three in three innings.

“The last outing threw up a bunch of zeroes,” Red Sox Manager Ron Roenicke said. “It’s just hard to say what’s going to happen from game to game.”

IN THE WEB

Godley had some bad luck mixed in with a few pitches that he can’t blame on anyone but himself.

Tampa Bay’s first run scored when first baseman Michael Chavis cleanly fielded a bases-loaded grounder but the ball got stuck in the webbing of his glove, preventing him from doing anything but stepping on first. In the second, after Adames had already hit a 400-foot home run, Pillar lost a fly ball that would have been the third out. Brandon Lowe hit the next pitch 415 feet for a two-run homer.

Tsutsugo made it 6-0 with a 405-foot homer in the third, and then the Rays took an 8-0 lead in the fourth.

TRAINER’S ROOM

Red Sox: Outfielder Andrew Benintendi was placed on the injured list because of a strained rib cage. He was injured when he fell down trying to go from first to third on a single in Tuesday night’s game.