WASHINGTON — The Justice Department inspector general on Thursday castigated former FBI Director James Comey for his actions during the Hillary Clinton email investigation and found that other senior bureau officials showed a “willingness to take official action” to prevent Donald Trump from becoming president.

The 500-page report, which documents major missteps in one of the most politically charged cases in the FBI’s history, provides the most exhaustive account to date of bureau and Justice Department decision-making throughout the investigation of Clinton’s use of a private email server while she was secretary of state, particularly in the months just before she lost the presidential election to Trump.

The inspector general did not find evidence supporting assertions made by the president and his allies that political bias inside the FBI rigged the case to clear Clinton, but the report cited numerous instances of unprofessionalism, bias and misjudgment that hurt the bureau’s credibility. In particular, the report singled out lead agent Peter Strzok as showing anti-Trump bias that could have affected his thinking on the case during the immediate run-up to the 2016 election.

The report is a blistering rebuke of Comey, who has spent recent months on a book tour promoting his brand of ethical leadership. Inspector General Michael Horowitz accused Comey of insubordination, saying he flouted Justice Department practices when he decided that only he had the authority and credibility to make key decisions and speak for the agency.

Comey made a “serious error of judgment” in sending a letter to Congress on Oct. 28, 2016, announcing that he was reopening the investigation of Clinton’s use of the server while secretary of state, the report found, and called it “extraordinary that Comey assessed that it was best” for him not to speak directly with either the attorney general or the deputy attorney general about his decision beforehand.

Some senior bureau officials, the report found, exhibited a disturbing “willingness to take official action” to hurt Trump’s chances of becoming president.

Perhaps the most damaging revelation in the report is a previously unreported text message in which Strzok, a key investigator on both the Clinton email case and the investigation of Russia and the Trump campaign, assured an FBI lawyer in August 2016 that “we’ll stop” Trump from making it to the White House.

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Trump was “not ever going to become president, right? Right?!” the lawyer, Lisa Page, wrote to Strzok.

“No. No he won’t. We’ll stop it,” Strzok responded. Page and Strzok were romantically involved and used their work phones to engage in long-running text discussions of various work and personal topics, according to people familiar with the case.

In a message posted to Twitter on Thursday afternoon, Comey wrote: “I respect the DOJ IG office, which is why I urged them to do this review. The conclusions are reasonable, even though I disagree with some. People of good faith can see an unprecedented situation differently. I pray no Director faces it again. Thanks to IG’s people for hard work.”

White House press secretary Sarah Huckabee Sanders said the report “reaffirmed the president’s suspicions about Comey’s conduct and the political bias among some of the members of the FBI.”

In a statement, Attorney General Jeff Sessions said the “significant errors” cited in the report took place during the Obama administration.

“Accordingly, this report must be seen as an opportunity for the FBI – long considered the world’s premier investigative agency – and all of us at the Department to learn from past mistakes,” Sessions said.

Sessions said that a new leadership team brought in by Comey’s replacement, FBI Director Christopher Wray, was “one in which the American people can have confidence.”

The attorney general suggested that others could be ousted in the wake of the report. Several officials said Strzok, in particular, could be fired or forced to resign in coming days.

Strzok’s lawyer, Aitan Goelman, called the report “critically flawed” for suggesting that his client’s political views might have influenced the FBI’s weeks-long delay in reopening the Clinton case in October 2016.

“Special Agent Strzok in particular was consistently thorough and aggressive, sometimes to the point that put him at odds with senior officials at the Department of Justice,” Goelman said.

The inspector general found that other FBI personnel also exchanged unprofessional and politically biased messages, singling out two unidentified agents and one lawyer for review and possible punishment by FBI administrators.

At a news conference, Wray said that he was “disappointed” by the conduct described in the report and that some employees would be subject to a disciplinary review. He pledged that the bureau would learn from the findings by training all of its executives and employees “so those mistakes will never be repeated.”

The FBI also will review how it handles recusals and will conduct an internal review “so that every sensitive investigation is conducted to the FBI’s highest standards.”

The report aimed to define once and for all what the FBI and Justice Department did correctly and what was wrong in the Clinton probe, but partisans are likely to seize on different findings to buttress their long-held views about that investigation.

For Trump, the report provides chapter upon chapter of fresh ammunition for his attacks on the FBI, which he has accused of political bias in investigating whether any of his campaign associates may have conspired with Russia to influence the 2016 election.

To Clinton and her supporters, who have long argued that Comey’s decisions robbed her of an election victory, the report is likely to be received as bitter vindication of her claims that the FBI director veered far beyond official policy in speaking publicly about her case, and reopening it in the final days before the election.

Partisans on both sides sought to cast the report to their advantage even before it was formally released.

“The stark conclusion we draw after reviewing this report is that the FBI’s actions helped Donald Trump become President,” Reps. Jerrold Nadler, D-N.Y., and Elijah Cummings, D-Md., said in a joint statement. “As we warned before the election, Director Comey had a double-standard: he spoke publicly about the Clinton investigation while keeping secret from the American people the investigation of Donald Trump and Russia.”

Rep. Mark Meadows, R-N.C., chairman of the House Freedom Caucus and a key Trump ally on Capitol Hill, said, “It appears at least five individuals that were involved in the Hillary Clinton investigation went on to investigate aspects of Russia, and when you have bias associated with that, it’s deeply troubling.”

Trump offered no immediate reaction after being briefed on the report before its formal release, but he fired off a pair of tweets renewing his attack on the Russia investigation, which he called a “pile of garbage.”

In a speech on the Senate floor, Minority Leader Chuck Schumer, D-N.Y., sought to preempt any claims by Trump that the report would show that bias against him by FBI officials has affected the Russia probe.

“There is no reason – no reason – to believe that it will provide any basis to call the special counsel’s work into question,” Schumer said. “The IG report concerns an entirely separate investigation from the Russia probe that special counsel Mueller is conducting.”

The inspector general concluded that Strzok’s text, along with others disparaging Trump, “is not only indicative of a biased state of mind but, even more seriously, implies a willingness to take official action to impact the presidential candidate’s electoral prospects.”

The messages “potentially indicated or created the appearance that investigative decisions were impacted by bias or improper considerations,” the inspector general wrote.

Strzok told investigators he believed the message “was intended to reassure Page that Trump would not be elected, not to suggest that he would do something to impact the investigation,” according to the report. Both he and Page generally defended their messages as instances of sharing personal opinions that did not affect their work.

“I’m an American. We have the First Amendment. I’m entitled to an opinion,” Page told investigators.

Even that defense, however, undercuts Comey, who had long proclaimed that his investigators “don’t give a rip about politics.”

Horowitz has been working for nearly a year and a half to assess the bureau’s handling of the Clinton email investigation and the bureau’s actions in the months leading up to the election, and all of Washington has eagerly been awaiting his findings. The president, who was briefed on the report before it was released publicly, has vigorously criticized Comey and the FBI.

Trump is all but certain to use the findings to renew those assaults, and potentially take aim at Special Counsel Robert Mueller. Strzok served as Mueller’s lead agent on the Russia probe until last July, when he was removed after the discovery of the text messages.

Horowitz also concluded that there was no evidence that political bias infected Comey’s thinking, even as he criticized individual steps Comey took. The report, for example, called Comey’s July 2016 public recommendation that Clinton not be charged an “extraordinary and insubordinate” move, because Comey did not even tell then-Attorney General Loretta Lynch what he was about to do. But it added, “We found no evidence that Comey’s statement was the result of bias or an effort to influence the election.”

Comey was not the only official to face criticism. The report chided Lynch for indecision after meeting with former president Bill Clinton on the tarmac of the Phoenix airport in the late stages of the campaign. She neither recused herself from the case to avoid the appearance of impropriety nor asserted herself more vigorously as Comey seized command.

Page and Strzok are not the only FBI officials assigned to the Clinton email probe who were found to have exchanged personal messages indicating either an animus against Trump or frustration with the fact that the FBI was investigating Clinton. The report identified five officials with some connection to the email probe who were expressing political views, faulting them for having brought “discredit to themselves, sowed doubt about the FBI’s handling of the midyear investigation, and impacted the reputation of the FBI.” The midyear investigation refers to the Clinton email probe.

“The messages cast a cloud over the FBI investigations to which these employees were assigned,” Horowitz alleged. “Ultimately the consequences of these actions impact not only the senders of these messages but also other who worked on these investigation and, indeed, the entire FBI.”

The inspector general wrote that he had referred the information regarding the five individuals who exchanged politically charged messages “to the FBI for its handling and consideration of whether the messages . . . violates the FBI’s Offense Code of Conduct.”

The report took particular aim at FBI officials investigating Clinton’s email server for moving slowly after agents in the New York field office discovered messages on the laptop of disgraced former congressman Anthony Weiner that might be relevant to their case.

By no later than Sept. 29, 2016, the inspector general alleged, the bureau had learned “virtually every fact” it would cite as justification late the next month to search Weiner’s laptop for messages of Clinton and top aide Huma Abedin.

The inspector general derided the bureau’s reasons for not moving more quickly – that agents were waiting for additional information from New York, that they could not move without a warrant and that investigators were more focused on the Russia case – as “unpersuasive,” “illogical” and inconsistent with their assertion that they would leave no stone unturned in investigating Clinton.

The report also faulted the bureau for assigning essentially the same personnel to the Russia and Clinton teams, and singled out Strzok, suggesting his anti-Trump views might have played a role in his not acting more expeditiously on the new lead.

“Under these circumstances, we did not have confidence that Strzok’s decision to prioritize the Russia investigation over following up on the midyear-related investigative lead discovered on the Weiner laptop was free from bias,” the report said.

The report determined that several FBI investigators – including Comey – also broke bureau protocol by using “personal email accounts for official government business.”

The inspector found five instances in which Comey either drafted official messages on or forwarded emails to his personal account, and at least two instances in which Strzok used his personal email for official business – including one “most troubling” instance on Oct. 29, 2016, when he forwarded “an email about the proposed search warrant the midyear team was seeking on the Weiner laptop” from his FBI account to his personal email.

The discovery is ironic, given that the FBI was exploring Clinton’s own use of a personal email server for work-related business and whether classified information traversed her server.