CHICAGO — Pinch-hitter J.B. Shuck had a go-ahead RBI single in the eighth inning Saturday to give the Chicago White Sox their first win of the season, 5-4 over the Minnesota Twins.

Shuck lined a 1-1 pitch from reliever Blaine Boyer (0-1) with two outs, scoring Alexei Ramirez. Conor Gillaspie was thrown out at the plate as he tried to score from second.

Former Yankees closer David Robertson struck out the side in the ninth for his first save with Chicago. The White Sox lost their first four games.

Left-hander Zach Duke (1-0) worked a scoreless eighth for the win.

In his first home start for the White Sox, Jeff Samardzija gave up four runs and eight hits in seven innings. He struck out six without walking a batter.

White Sox first baseman Adam LaRoche broke out of a 1-for-14 slump with his first home run of the season, leading off the second against Mike Pelfrey.

MARINERS 5, ATHLETICS 4, 11 innings: Nelson Cruz hit his first home run for Seattle and Brad Miller threw out a runner at the plate in the 10th inning and doubled in the go-ahead run in the 11th, lifting Seattle over Oakland.

Cruz, signed to a $57 million, four-year contract as a free agent, hit a three-run drive in the eighth off Dan Otero to put the Mariners in front 4-2. Oakland tied the score in the bottom half on RBI doubles by Ben Zobrist off Danny Farquhar and Brett Lawrie against Carson Smith.

Logan Morrison singled against Fernando Abad (0-1) leading off the 11th, advanced on Dustin Ackley’s sacrifice and scored when Miller sliced a fastball into the left-field corner for an opposite-field hit.

TIGERS 9, INDIANS 6: Ian Kinsler hit an RBI single and Yoenis Cespedes doubled in two runs during a four-run ninth inning as Detroit stayed unbeaten with a win at Cleveland.

Kinsler’s fourth hit — a single off closer Cody Allen (0-1) — snapped a 5-all tie and helped the Tigers improve to 5-0 for the first time since 2006. The Tigers had to rally twice after Cleveland’s Jerry Sands delivered a pair of clutch doubles.

Miguel Cabrera also had four hits for Detroit, which has now outscored its opponents 39-11.

Ian Krol (1-0) got the win despite giving up an eighth-inning double to Sands.

Indians catcher Yan Gomes sustained a potentially serious injury to his right leg in the ninth.

NATIONAL LEAGUE

CARDINALS 4, REDS 1: Matt Adams delivered his first home run of the season and St. Louis snapped Cincinnati’s season-opening winning streak at four with a win in Cincinnati.

Kolten Wong drove in a run with a sacrifice fly, Jhonny Peralta and Yadier Molina added ninth-inning run-scoring singles and Michael Wacha pitched into the seventh inning to get the win in his first appearance of the season.

Wacha (1-0) shook off Todd Frazier’s first-inning home run to go 61/3 innings, allowing five hits and one run with a walk and two strikeouts. He stranded a runner in scoring position in each of his last four full innings.

The Reds left five runners in scoring position.

Trevor Rosenthal, the Cardinals’ fifth relief pitcher, got the last five outs for his second save.

INTERLEAGUE

RAYS 2, MARLINS 0: Chris Archer pitched seven crisp innings, and Tampa Bay beat host Miami.

Archer (1-1) allowed one hit and one walk, with the latter runner erased trying to steal, while throwing only 84 pitches. Two relievers completed the two-hitter, with Brad Boxberger pitching the ninth for his second save in two chances.